Scientific Name: Panthera tigris altaica
Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Laurasiatheria-> Carnivora-> Feliformia-> Felidae-> Pantherinae-> Panthera-> Panthera tigris
Summary: The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015] [NCBI] [Proteinatlas]
Data set information
| Project | Date | Technology | Tissue | Condition | Cell | PMID/DOI |
|---|---|---|---|---|---|---|
| Vthunter_0023 | 2021.04 | 10X Genomics | Heart | Normal | 16479 | Link |
| Vthunter_0024 | 2021.04 | 10X Genomics | Kidney | Normal | 3483 | Link |
| Vthunter_0025 | 2021.04 | 10X Genomics | Liver | Normal | 10237 | Link |
| Vthunter_0026 | 2021.04 | 10X Genomics | Lung | Normal | 14159 | Link |
| Vthunter_0027 | 2021.04 | 10X Genomics | Spleen | Normal | 33029 | Link |
| Vthunter_0057 | 2021.04 | iDrop | PBMC | Normal | 4755 | Link |
Featureplot of receptors
Expression: Ubiquitous expression in thyroid (RPKM 45.9), ovary (RPKM 36.3) and 24 other tissues
